Rich Thomas: Speed isn't everything, but speed plus power is pretty close, and Pacquiao has that. Although Mosley might land the odd hard shot during the fight, I can't see him scoring with the short combo of hard punches he would need to deter Pacquiao. Coping with Pacquiao's lightning fists from all angles will force Mosley to cut his punch output, and if nothing else, that will pretty much dictate Pacquiao landing more leather and outpointing him.
Scott Levinson: Speed—a longtime hallmark of Mosley’s game just might be his weakness at this late stage of his career. Except for a few scant moments, Mayweather dominated Mosley with speed and Pacquiao is no slouch in that department. While still fast himself, Mosley will struggle to contain the whirlwind style of Pacquiao. It’s difficult to write off a man as talented and well-prepared as Mosley, especially as he is facing a do-or-die situation in his career. This just seems like a tough spot for the old lion. While this year has shown that anything can happen, I just can’t believe a guy pushing 40 with 2 official wins in his last 5 fights is the right candidate to pull off this type of feat—even if it is a great like Sugar Shane. I like Pacquiao somewhere between the 9th and 11th rounds.
Jake Emen: A fight between prime incarnations of Mosley and Pacquiao at either 135 or 147 lbs would be phenomenal. This isn't the fight that we'll be seeing, however. Mosley won't be able to stay out of harm's way, and he won't be able to tag the speedier Pacquiao flush , either. Shane has never been adept at bouncing back from early struggles in a fight to turn things around late, and that is a terrible sign of things to come against Pacquiao. Pacquiao won't be able to take Shane out, but the accumulation of punishment will leave Shane humbled, broken down and altogether battered after a full 12 rounds.